3D liver model for surgical planning
Several models needed for the virtual liver are being developed: (i) a 3D anatomical model that captures the geometry of the liver surfaces and can be morphed into a patient-specific image dataset, (ii) a macro-circulation model on which the fluid flow equations are solved, (iii) a micro-circulation model that will enable the study of tissue regeneration post-surgery.
The figure below shows (a) the 8 anatomically defined Couinaud segments, (b) bounding boxes, based on these segments, that (c) can be used to morph the generic vascular model to fit patient specific fiducial markers.
A blood flow model has been developed that allows rapid computation of pressures and flows in the vascular system of the liver, given suitable boundary conditions, to predict the outcome of surgical interventions e.g. left or right lobectomy (see below). This will be available through the GUI described under the next milestone.